N2-iBu-2’,3’-bis-O-TBDMS guanosine

Modify Date: 2024-04-11 17:20:02

N2-iBu-2’,3’-bis-O-TBDMS guanosine Structure
N2-iBu-2’,3’-bis-O-TBDMS guanosine structure
Common Name N2-iBu-2’,3’-bis-O-TBDMS guanosine
CAS Number 79974-70-2 Molecular Weight 581.85
Density N/A Boiling Point N/A
Molecular Formula C26H47N5O6Si2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N2-iBu-2’,3’-bis-O-TBDMS guanosine


N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name N2-iBu-2’,3’-bis-O-TBDMS guanosine

 N2-iBu-2’,3’-bis-O-TBDMS guanosine Biological Activity

Description N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C26H47N5O6Si2
Molecular Weight 581.85
InChIKey VZMILHMVPGBTBQ-DYVMYPEFSA-N
SMILES CC(C)C(=O)Nc1nc2c(ncn2C2OC(CO)C(O[Si](C)(C)C(C)(C)C)C2O[Si](C)(C)C(C)(C)C)c(=O)[nH]1
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