ACG416B

Modify Date: 2025-07-25 13:06:17

ACG416B Structure
ACG416B structure
Common Name ACG416B
CAS Number 795316-15-3 Molecular Weight 708.53
Density N/A Boiling Point N/A
Molecular Formula C38H36Br2N4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ACG416B


ACG416B (compound 18) is a potent inhibitor of ChoK (choline kinase) with an IC50 of 0.4 μM. ACG416B renders higher ChoK inhibitory and antiproliferative activities against the HT-29 human colon cancer cell[1].

 Names

Name ACG416B

 ACG416B Biological Activity

Description ACG416B (compound 18) is a potent inhibitor of ChoK (choline kinase) with an IC50 of 0.4 μM. ACG416B renders higher ChoK inhibitory and antiproliferative activities against the HT-29 human colon cancer cell[1].
Related Catalog
Target

ChoK[1]

References

[1]. onejo-García A, et al. Influence of the linker in bispyridium compounds on the inhibition of human choline kinase. J Med Chem. 2004 Oct 21;47(22):5433-40.

 Chemical & Physical Properties

Molecular Formula C38H36Br2N4
Molecular Weight 708.53
InChIKey NOXDPLVCKHQSFW-UHFFFAOYSA-L
SMILES CN(c1ccccc1)c1cc[n+](Cc2cccc(-c3cccc(C[n+]4ccc(N(C)c5ccccc5)cc4)c3)c2)cc1.[Br-].[Br-]
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