ACG416B

Names

[ Name ]:
ACG416B

Biological Activity

[Description]:

ACG416B (compound 18) is a potent inhibitor of ChoK (choline kinase) with an IC50 of 0.4 μM. ACG416B renders higher ChoK inhibitory and antiproliferative activities against the HT-29 human colon cancer cell[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

ChoK[1]

[References]

[1]. onejo-García A, et al. Influence of the linker in bispyridium compounds on the inhibition of human choline kinase. J Med Chem. 2004 Oct 21;47(22):5433-40.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₈H₃₆Br₂N₄

[ Molecular Weight ]:
708.53

Related Compounds

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