TASIN-1

Modify Date: 2024-01-03 12:52:57

TASIN-1 Structure
TASIN-1 structure
Common Name TASIN-1
CAS Number 792927-06-1 Molecular Weight 352.491
Density 1.2±0.1 g/cm3 Boiling Point 480.0±55.0 °C at 760 mmHg
Molecular Formula C18H28N2O3S Melting Point N/A
MSDS N/A Flash Point 244.1±31.5 °C

 Use of TASIN-1


TASIN-1 is a selective inhibitor of truncated APC gene (adenomatous polyposis coli gene) and exerts cytotoxic effects through inhibition of cholesterol biosynthesis. TASIN-1 represents a potential therapeutic strategy for prevention and intervention in CRC with mutant APC[1].

 Names

Name TASIN-1
Synonym More Synonyms

 TASIN-1 Biological Activity

Description TASIN-1 is a selective inhibitor of truncated APC gene (adenomatous polyposis coli gene) and exerts cytotoxic effects through inhibition of cholesterol biosynthesis. TASIN-1 represents a potential therapeutic strategy for prevention and intervention in CRC with mutant APC[1].
Related Catalog
References

[1]. Zhang L, et al. Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. Sci Transl Med. 2016 Oct 19;8(361):361ra140.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 480.0±55.0 °C at 760 mmHg
Molecular Formula C18H28N2O3S
Molecular Weight 352.491
Flash Point 244.1±31.5 °C
Exact Mass 352.182068
LogP 4.12
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.557

 Synonyms

1,4'-Bipiperidine, 1'-[(4-methoxyphenyl)sulfonyl]-4-methyl-
1'-[(4-Methoxyphenyl)sulfonyl]-4-methyl-1,4'-bipiperidine