Polygalasaponin XXXI
Modify Date: 2024-01-02 16:18:55
Polygalasaponin XXXI structure
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Common Name | Polygalasaponin XXXI | ||
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| CAS Number | 79103-90-5 | Molecular Weight | 1589.670 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C75H112O36 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Polygalasaponin XXXIPolygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection[1]. |
| Name | onjisaponin F |
|---|---|
| Synonym | More Synonyms |
| Description | Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection[1]. |
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| Related Catalog | |
| In Vitro | Polygalasaponin XXXI (Onjisaponin F) also enhances anti-HA IgA and IgG Ab titers in the nasal wash, whereas Onjisaponins E and G enhances only anti-HA IgA Ab titer significantly. Polygalasaponin XXXI can induce protective immunity against intranasal infection by influenza virus[1]. Polygalasaponin XXXI (Onjisaponin F) (1 or 10 µg/mL) also induces ChAT mRNA level in rat basal forebrain cells[2]. |
| In Vivo | Intranasal vaccination with Polygalasaponin XXXI (Onjisaponin F) inhibits proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C75H112O36 |
| Molecular Weight | 1589.670 |
| Exact Mass | 1588.693359 |
| PSA | 542.80000 |
| LogP | 4.95 |
| Index of Refraction | 1.651 |
| Polygalasaponin XXXI |
| β-D-Galactopyranose, O-α-L-arabinopyranosyl-(1->3)-O-α-D-xylopyranosyl-(1->4)-O-6-deoxy-3-O-[(2S,3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-α-L-mannopyranosyl-(1->2)-6 -deoxy-1-O-[(2β,3β)-3-(β-D-glucopyranosyloxy)-2,24,27-trihydroxy-24,28-dioxoolean-12-en-28-yl]-4-O-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]- |
| α-L-Arabinopyranosyl-(1->3)-α-D-xylopyranosyl-(1->4)-6-deoxy-3-O-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-α-L-mannopyranosyl-(1->2)-6-deoxy-1-O-[(2β,3β)-3-(be ta-D-glucopyranosyloxy)-2,24,27-trihydroxy-24,28-dioxoolean-12-en-28-yl]-4-O-[(2E)-3-(3,4,5-trimethoxyphenyl)-2-propenoyl]-β-D-galactopyranose |