Lenalidomide-4-aminomethyl
Modify Date: 2025-09-16 23:15:04
Lenalidomide-4-aminomethyl structure
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Common Name | Lenalidomide-4-aminomethyl | ||
|---|---|---|---|---|
| CAS Number | 790652-68-5 | Molecular Weight | 273.29 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H15N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Lenalidomide-4-aminomethylLenalidomide-4-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl can be connected to the ligand for protein by a linker to form PROTAC[1]. |
| Name | Lenalidomide-4-aminomethyl |
|---|---|
| Synonym | More Synonyms |
| Description | Lenalidomide-4-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl can be connected to the ligand for protein by a linker to form PROTAC[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C14H15N3O3 |
|---|---|
| Molecular Weight | 273.29 |
| InChIKey | LVJSNECQDVVLEF-UHFFFAOYSA-N |
| SMILES | NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O |
| Hazard Codes | Xi |
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| MFCD32201918 |