4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride

Modify Date: 2025-09-27 15:05:10

4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride Structure
4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride structure
Common Name 4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride
CAS Number 788824-64-6 Molecular Weight 391.63
Density N/A Boiling Point N/A
Molecular Formula C14H15ClINO2 Melting Point 209-211ºC
MSDS N/A Flash Point N/A

 Use of 4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride


3-Iodothyronamine (hydrochloride) is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure[1].

 Names

Name 4-[4-(2-aminoethyl)-2-iodophenoxy]phenol,hydrochloride
Synonym More Synonyms

  Biological Activity

Description 3-Iodothyronamine (hydrochloride) is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure[1].
Related Catalog
References

[1]. Hart ME, et al. Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. J Med Chem. 2006 Feb 9;49(3):1101-12.  

 Chemical & Physical Properties

Melting Point 209-211ºC
Molecular Formula C14H15ClINO2
Molecular Weight 391.63
Exact Mass 390.983582
PSA 55.48000
LogP 4.79260

 Safety Information

Hazard Codes C

 Synonyms

Phenol,4-[4-(2-aminoethyl)-2-iodophenoxy]-,hydrochloride
2-[4-(4-Hydroxyphenoxy)-3-iodophenyl]ethanaminium chloride
4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride
3-Iodothyronamine Hydrochloride
Phenol, 4-[4-(2-aminoethyl)-2-iodophenoxy]-, hydrochloride (1:1)
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.