Ecliptasaponin A

Modify Date: 2024-01-03 12:43:13

Ecliptasaponin A structure	Common Name	Ecliptasaponin A
	CAS Number	78285-90-2	Molecular Weight	634.840
	Density	1.27±0.1 g/cm3	Boiling Point	752.6±60.0 °C at 760 mmHg
	Molecular Formula	C₃₆H₅₈O₉	Melting Point	237～238℃
	MSDS	USA	Flash Point	228.6±26.4 °C

Use of Ecliptasaponin A

Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate[1]. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory[2].

Name	echinocystic acid-3-glucoside
Synonym	More Synonyms

Description	Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate[1]. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Du G, et al. Validated UPLC-MS/MS method for quantification of seven compounds in rat plasma and tissues: Application to pharmacokinetic and tissue distribution studies in rats after oral administration of extract of Eclipta prostrata L. Biomed Chromatogr. 2018 Jun;32(6):e4191. [2]. You XY, et al. Preventive effects of Ecliptae Herba extract and its component, ecliptasaponin A, on bleomycin-induced pulmonary fibrosis in mice. J Ethnopharmacol. 2015 Dec 4;175:172-80.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Du G, et al. Validated UPLC-MS/MS method for quantification of seven compounds in rat plasma and tissues: Application to pharmacokinetic and tissue distribution studies in rats after oral administration of extract of Eclipta prostrata L. Biomed Chromatogr. 2018 Jun;32(6):e4191.

[2]. You XY, et al. Preventive effects of Ecliptae Herba extract and its component, ecliptasaponin A, on bleomycin-induced pulmonary fibrosis in mice. J Ethnopharmacol. 2015 Dec 4;175:172-80.

Density	1.27±0.1 g/cm3
Boiling Point	752.6±60.0 °C at 760 mmHg
Melting Point	237～238℃
Molecular Formula	C₃₆H₅₈O₉
Molecular Weight	634.840
Flash Point	228.6±26.4 °C
Exact Mass	634.408081
PSA	156.91000
LogP	5.61
Vapour Pressure	0.0±5.7 mmHg at 25°C
Index of Refraction	1.595
Storage condition	2-8°C
Water Solubility	Insuluble (1.1E-3 g/L) (25 ºC)