Ecliptasaponin A

Names

[ Name ]:
Ecliptasaponin A

[Synonym ]:
Gleditsoside B
Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-16-hydroxy-, (3β,16α)-
(3β,16α)-3-(β-D-Glucopyranosyloxy)-16-hydroxyolean-12-en-28-oic acid
Gleditschoside B
Echynocystinsaeure-monosid
Echinocystic acid-3-O-glucoside
Ecliptasaponin A
EINECS 278-887-0

Biological Activity

[Description]:

Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate[1]. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory[2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Du G, et al. Validated UPLC-MS/MS method for quantification of seven compounds in rat plasma and tissues: Application to pharmacokinetic and tissue distribution studies in rats after oral administration of extract of Eclipta prostrata L. Biomed Chromatogr. 2018 Jun;32(6):e4191.

[2]. You XY, et al. Preventive effects of Ecliptae Herba extract and its component, ecliptasaponin A, on bleomycin-induced pulmonary fibrosis in mice. J Ethnopharmacol. 2015 Dec 4;175:172-80.

Chemical & Physical Properties

[ Density]:
1.27±0.1 g/cm3

[ Boiling Point ]:
752.6±60.0 °C at 760 mmHg

[ Melting Point ]:
237～238℃

[ Molecular Formula ]:
C₃₆H₅₈O₉

[ Molecular Weight ]:
634.840

[ Flash Point ]:
228.6±26.4 °C

[ Exact Mass ]:
634.408081

[ PSA ]:
156.91000

[ LogP ]:
5.61

[ Vapour Pressure ]:
0.0±5.7 mmHg at 25°C

[ Index of Refraction ]:
1.595

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Insuluble (1.1E-3 g/L) (25 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29389090