2-Methyl-5-HT maleate

Modify Date: 2024-01-06 20:51:47

2-Methyl-5-HT maleate Structure
2-Methyl-5-HT maleate structure
Common Name 2-Methyl-5-HT maleate
CAS Number 78263-91-9 Molecular Weight 306.31400
Density N/A Boiling Point N/A
Molecular Formula C15H18N2O5 Melting Point N/A
MSDS USA Flash Point N/A

 Use of 2-Methyl-5-HT maleate


2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT maleate is shown to display anti-depressive-like effects[1].

 Names

Name 2-methylserotonin maleate salt
Synonym More Synonyms

 2-Methyl-5-HT maleate Biological Activity

Description 2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT maleate is shown to display anti-depressive-like effects[1].
Target

5-HT3 Receptor

In Vivo 2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) (i.p.; 3 mg/kg; 45 minutes) significantly decreases time of immobility as compared to controls thus showing anti-depressive-like effects[1]. Animal Model: Male Sprague-Dawley rats[1] Dosage: 3 mg/kg Administration: I.p.; 45 minutes Result: Significantly decreased time of immobility thus showing anti-depressive-like effects.
References

[1]. Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem Behav. 2016 May;144:78-84.

 Chemical & Physical Properties

Molecular Formula C15H18N2O5
Molecular Weight 306.31400
Exact Mass 306.12200
PSA 136.64000
LogP 2.09520

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

MFCD00082467
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