Huwentoxin I

Modify Date: 2025-08-26 11:36:47

Huwentoxin I Structure
Huwentoxin I structure
Common Name Huwentoxin I
CAS Number 769973-37-7 Molecular Weight 3750.36
Density N/A Boiling Point N/A
Molecular Formula C161H246N48O44S6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Huwentoxin I


Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively[1].

 Names

Name Huwentoxin I

 Huwentoxin I Biological Activity

Description Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively[1].
Related Catalog
References

[1]. Wang M, et al. The effects of huwentoxin-I on the voltage-gated sodium channels of rat hippocampal and cockroach dorsal unpaired median neurons. Peptides. 2012 Mar;34(1):19-25.  

 Chemical & Physical Properties

Molecular Formula C161H246N48O44S6
Molecular Weight 3750.36
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