Piptocarphin F

Modify Date: 2025-08-25 14:41:55

Piptocarphin F Structure
Piptocarphin F structure
Common Name Piptocarphin F
CAS Number 76215-53-7 Molecular Weight 408.44
Density 1.3g/cm3 Boiling Point 573.4ºC at 760 mmHg
Molecular Formula C21H28O8 Melting Point N/A
MSDS N/A Flash Point 197ºC

 Use of Piptocarphin F


Piptocarphin F (Compound 5) is a sesquiterpene lactone. Piptocarphin F shows cytotoxic activity on human leukemia cell lineHL-60 (IC50=5.69 μmol*L-1)[1].

 Names

Name piptocarphin f b822833k330

 Piptocarphin F Biological Activity

Description Piptocarphin F (Compound 5) is a sesquiterpene lactone. Piptocarphin F shows cytotoxic activity on human leukemia cell lineHL-60 (IC50=5.69 μmol*L-1)[1].
Related Catalog
References

[1]. LIAO, S.-G., et al. Cytotoxic sesquiterpene lactones from Vernonia bockiana. Chinese Journal of Natural Medicines. 2012 May 20;10(3):230–233.

 Chemical & Physical Properties

Density 1.3g/cm3
Boiling Point 573.4ºC at 760 mmHg
Molecular Formula C21H28O8
Molecular Weight 408.44
Flash Point 197ºC
Exact Mass 408.17800
PSA 111.52000
LogP 1.66050
Index of Refraction 1.565
InChIKey UBMOPFJLLXVNIM-ZUQHRPQWSA-N
SMILES C=C(C)C(=O)OC1CC(C)(O)C2(O)CCC(C)(C=C3OC(=O)C(COCC)=C31)O2

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UD3467000
CHEMICAL NAME :
2-Propenoic acid, 2-methyl-, 2,4,5,6,7,8,9,10-octahydro-6,7-dihydroxy-6,10-dimethy l-3- (ethoxymethyl)-2-oxo-7,10-epoxycyclodeca(b)furan-4-yl ester, (4S-(4R*,6S*,7S*,10R*,11E))-
CAS REGISTRY NUMBER :
76215-53-7
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H28-O8
MOLECULAR WEIGHT :
408.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5105 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 12,443,1985
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