Piptocarphin F

Modify Date: 2025-08-25 14:41:55

Piptocarphin F Structure
Piptocarphin F structure
Common Name Piptocarphin F
CAS Number 76215-53-7 Molecular Weight 408.44
Density 1.3g/cm3 Boiling Point 573.4ºC at 760 mmHg
Molecular Formula C21H28O8 Melting Point N/A
MSDS N/A Flash Point 197ºC

 Use of Piptocarphin F


Piptocarphin F (Compound 5) is a sesquiterpene lactone. Piptocarphin F shows cytotoxic activity on human leukemia cell lineHL-60 (IC50=5.69 μmol*L-1)[1].

 Names

Name piptocarphin f b822833k330

 Piptocarphin F Biological Activity

Description Piptocarphin F (Compound 5) is a sesquiterpene lactone. Piptocarphin F shows cytotoxic activity on human leukemia cell lineHL-60 (IC50=5.69 μmol*L-1)[1].
Related Catalog
References

[1]. LIAO, S.-G., et al. Cytotoxic sesquiterpene lactones from Vernonia bockiana. Chinese Journal of Natural Medicines. 2012 May 20;10(3):230–233.

 Chemical & Physical Properties

Density 1.3g/cm3
Boiling Point 573.4ºC at 760 mmHg
Molecular Formula C21H28O8
Molecular Weight 408.44
Flash Point 197ºC
Exact Mass 408.17800
PSA 111.52000
LogP 1.66050
Index of Refraction 1.565

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UD3467000
CHEMICAL NAME :
2-Propenoic acid, 2-methyl-, 2,4,5,6,7,8,9,10-octahydro-6,7-dihydroxy-6,10-dimethy l-3- (ethoxymethyl)-2-oxo-7,10-epoxycyclodeca(b)furan-4-yl ester, (4S-(4R*,6S*,7S*,10R*,11E))-
CAS REGISTRY NUMBER :
76215-53-7
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H28-O8
MOLECULAR WEIGHT :
408.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5105 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 12,443,1985
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