Solithromycin
Modify Date: 2024-01-08 13:52:05
Solithromycin structure
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Common Name | Solithromycin | ||
|---|---|---|---|---|
| CAS Number | 760981-83-7 | Molecular Weight | 845.009 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 969.2±75.0 °C at 760 mmHg | |
| Molecular Formula | C43H65FN6O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 539.9±37.1 °C | |
Use of SolithromycinSolithromycin is a novel fluoroketolide with improved antimicrobial effectiveness.Target: AntibacterialSolithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis. The mean 50% inhibitory concentrations (IC50s) for Solithromycin inhibition of cell viability, protein synthesis, and growth rate were 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively. |
| Name | Solithromycin |
|---|---|
| Synonym | More Synonyms |
| Description | Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness.Target: AntibacterialSolithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis. The mean 50% inhibitory concentrations (IC50s) for Solithromycin inhibition of cell viability, protein synthesis, and growth rate were 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 969.2±75.0 °C at 760 mmHg |
| Molecular Formula | C43H65FN6O10 |
| Molecular Weight | 845.009 |
| Flash Point | 539.9±37.1 °C |
| Exact Mass | 844.474609 |
| PSA | 197.87000 |
| LogP | 3.44 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.591 |
| Storage condition | -20℃ |
| Solithromycin |
| (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-Aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4 ;,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside |
| 2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 1-[4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl]-4-ethyl-7-fluorooctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-[[3,4,6-trideox ;y-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)- |