(S)-Nicardipine

Modify Date: 2025-08-27 14:23:24

(S)-Nicardipine Structure
(S)-Nicardipine structure
 Common Name (S)-Nicardipine
CAS Number 76093-36-2 Molecular Weight 479.52
Density N/A Boiling Point N/A
Molecular Formula C26H29N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-Nicardipine


(S)-Nicardipine ((S)-YC-93 free base) is the less active S enantiomer of Nicardipine. Nicardipine is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure[1].

 Names

Name (S)-Nicardipine

 (S)-Nicardipine Biological Activity

Description (S)-Nicardipine ((S)-YC-93 free base) is the less active S enantiomer of Nicardipine. Nicardipine is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure[1].
Related Catalog
References

[1]. Charnet P, et al. Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers. Fundam Clin Pharmacol. 1987;1(6):413-31.

 Chemical & Physical Properties

Molecular Formula C26H29N3O6
Molecular Weight 479.52
InChIKey ZBBHBTPTTSWHBA-DEOSSOPVSA-N
SMILES COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1
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