Imanixil

Modify Date: 2024-01-14 15:47:21

Imanixil Structure
Imanixil structure
Common Name Imanixil
CAS Number 75689-93-9 Molecular Weight 394.35100
Density 1.428g/cm3 Boiling Point N/A
Molecular Formula C17H17F3N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Imanixil


Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates atherosclerosis development[1].

 Names

Name 4-amino-3-ethoxybenzenesulfonic acid

 Imanixil Biological Activity

Description Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates atherosclerosis development[1].
Related Catalog
References

[1]. Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63(9):1755-61.

 Chemical & Physical Properties

Density 1.428g/cm3
Molecular Formula C17H17F3N6O2
Molecular Weight 394.35100
Exact Mass 394.13700
PSA 113.24000
LogP 3.68610
Index of Refraction 1.601

 Synthetic Route

~%

Imanixil Structure

Imanixil

CAS#:75689-93-9

Literature: Kampe, Klaus-Dieter Angewandte Chemie, 1982 , vol. 94, # 7 p. 543 - 544

 Precursor & DownStream

Precursor  2

DownStream  0

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