2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Modify Date: 2024-01-31 08:54:57

2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol structure	Common Name	2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
	CAS Number	75059-23-3	Molecular Weight	339.37
	Density	1.78g/cm3	Boiling Point	681.5ºC at 760mmHg
	Molecular Formula	C₁₃H₁₇N₅O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

8-Allylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Name	2-(6-amino-8-prop-2-enylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Description	8-Allylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Density	1.78g/cm3
Boiling Point	681.5ºC at 760mmHg
Molecular Formula	C₁₃H₁₇N₅O₄S
Molecular Weight	339.37
Exact Mass	339.10000
PSA	164.84000
Index of Refraction	1.802

2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Use of 2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Names

Biological Activity

Chemical & Physical Properties