RU28362

Modify Date: 2025-08-26 16:04:19

RU28362 structure	Common Name	RU28362
	CAS Number	74915-64-3	Molecular Weight	352.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RU28362

RU28362 is a potent and selective glucocorticoid agonist. RU28362 increases the Bnip3 mRNA levels in neurons. RU28362 inhibits adrenocorticotrophic hormone (ACTH) and corticosterone secretion[1][2].

Name	ru 28362
Synonym	More Synonyms

Description	RU28362 is a potent and selective glucocorticoid agonist. RU28362 increases the Bnip3 mRNA levels in neurons. RU28362 inhibits adrenocorticotrophic hormone (ACTH) and corticosterone secretion[1][2].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
References	[1]. Sandau US, et al. Glucocorticoids exacerbate hypoxia-induced expression of the pro-apoptotic gene Bnip3 in the developing cortex. Neuroscience. 2007 Jan 19;144(2):482-94. [2]. Ginsberg AB, et al. Specific and time-dependent effects of glucocorticoid receptor agonist RU28362 on stress-induced pro-opiomelanocortin hnRNA, c-fos mRNA and zif268 mRNA in the pituitary. J Neuroendocrinol. 2006 Feb;18(2):129-38.

Description

RU28362 is a potent and selective glucocorticoid agonist. RU28362 increases the Bnip3 mRNA levels in neurons. RU28362 inhibits adrenocorticotrophic hormone (ACTH) and corticosterone secretion[1][2].

Related Catalog

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor

References

[1]. Sandau US, et al. Glucocorticoids exacerbate hypoxia-induced expression of the pro-apoptotic gene Bnip3 in the developing cortex. Neuroscience. 2007 Jan 19;144(2):482-94.

[2]. Ginsberg AB, et al. Specific and time-dependent effects of glucocorticoid receptor agonist RU28362 on stress-induced pro-opiomelanocortin hnRNA, c-fos mRNA and zif268 mRNA in the pituitary. J Neuroendocrinol. 2006 Feb;18(2):129-38.

Molecular Formula	C₂₃H₂₈O₃
Molecular Weight	352.47
Exact Mass	352.20400
PSA	57.53000
LogP	3.18560

11β,17β-dihydroxy-6,21-dimethyl-17α-pregna-1,4,6-trien-20-yn-3-one

RU28362

(11BETA,17BETA)-11,17-DIHYDROXY-6-METHYL-17-(1-PROPYNYL)-ANDROSTA-1,4,6-TRIEN-3-ONE

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RU28362

Use of RU28362

Names

RU28362 Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.