Antileishmanial agent-23

Modify Date: 2024-04-05 21:14:15

Antileishmanial agent-23 Structure
Antileishmanial agent-23 structure
Common Name Antileishmanial agent-23
CAS Number 745033-86-7 Molecular Weight 427.50
Density N/A Boiling Point N/A
Molecular Formula C20H17N3O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antileishmanial agent-23


Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei[1].

 Names

Name WAY-624876
Synonym More Synonyms

 Antileishmanial agent-23 Biological Activity

Description Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei[1].
Related Catalog
References

[1]. Ilari A, et al. Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors. Mol Pharm. 2018 Aug 6;15(8):3069-3078.  

 Chemical & Physical Properties

Molecular Formula C20H17N3O4S2
Molecular Weight 427.50

 Synonyms

1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]-
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