Diazepinomicin
Modify Date: 2025-08-25 12:09:16
Diazepinomicin structure
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Common Name | Diazepinomicin | ||
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| CAS Number | 733035-26-2 | Molecular Weight | 462.58100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H34N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DiazepinomicinDiazepinomicin (TLN-4601) is a secondary metabolite produced by Micromonospora sp. Diazepinomicin (TLN-4601) inhibits the EGF-induced Ras-ERK MAPK signaling pathway and induces apoptosis. An anti-tumor agent for K-Ras mutant models[1]. |
| Name | 1,3,10-trihydroxy-5-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]-11H-benzo[b][1,4]benzodiazepin-6-one |
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| Synonym | More Synonyms |
| Description | Diazepinomicin (TLN-4601) is a secondary metabolite produced by Micromonospora sp. Diazepinomicin (TLN-4601) inhibits the EGF-induced Ras-ERK MAPK signaling pathway and induces apoptosis. An anti-tumor agent for K-Ras mutant models[1]. |
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| Related Catalog | |
| Target |
Diazepinomicin (TLN-4601) inhibits the EGF-induced Ras-ERK MAPK signaling pathway post Ras prenylation and prior to MEK activation[1]. |
| References |
| Molecular Formula | C28H34N2O4 |
|---|---|
| Molecular Weight | 462.58100 |
| Exact Mass | 462.25200 |
| PSA | 98.48000 |
| LogP | 6.58100 |
| InChIKey | SALVHVNECODMJP-GNUCVDFRSA-N |
| SMILES | CC(C)=CCCC(C)=CCCC(C)=CCN1C(=O)c2cccc(O)c2Nc2c(O)cc(O)cc21 |
| BU-4664L |
| ECO-4601 |
| Diazepinomicin |
| TLN-4601 |
| UNII-YPH994Y0RF |