Guaiacol-d4

Modify Date: 2024-01-12 09:47:18

Guaiacol-d4 structure	Common Name	Guaiacol-d4
	CAS Number	7329-52-4	Molecular Weight	128.16200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇H₄D₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Guaiacol-d4

Guaiacol-d4 is the deuterium labeled Guaiacol[1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[2].

Name	2-methoxyphenol-3,4,5,6-d4

Description	Guaiacol-d4 is the deuterium labeled Guaiacol[1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Murakami Y, et al. Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and Guaiacol in macrophages stimulated with lipopolysaccharide. Anticancer Res. 2007 Mar-Apr;27(2):801-7.

Molecular Formula	C₇H₄D₄O₂
Molecular Weight	128.16200
Exact Mass	128.07800
PSA	29.46000
LogP	1.40080