Apovincaminic acid hydrochloride salt
Modify Date: 2025-08-27 13:22:55
Apovincaminic acid hydrochloride salt structure
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Common Name | Apovincaminic acid hydrochloride salt | ||
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| CAS Number | 72296-47-0 | Molecular Weight | 358.862 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H23ClN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Apovincaminic acid hydrochloride saltApovincaminic acid hydrochloride salt is an orally active and brain-penetrant main active metabolite of Vinpocetine (VP). Apovincaminic acid hydrochloride salt exerts a neuroprotective type of action[1][2]. |
| Name | (3α,16α)-Eburnamenine-14-carboxylic acid hydrochloride (1:1) |
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| Synonym | More Synonyms |
| Description | Apovincaminic acid hydrochloride salt is an orally active and brain-penetrant main active metabolite of Vinpocetine (VP). Apovincaminic acid hydrochloride salt exerts a neuroprotective type of action[1][2]. |
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| Related Catalog | |
| In Vivo | Apovincaminic acid (10 mg/kg; i.p. twice daily for 4 days) effectively attenuates the behavioral deficits, and significantly decreases lesion size and the region of microglia activation[1]. Apovincaminic acid (10 mg/kg; p.o.) is absorbed 50% of the dose comparing with i.v. administration in rats[2]. Animal Model: Male Harlan‐Wistar rats (300-400 g) are injected NMDA[1] Dosage: 10 mg/kg Administration: I.p. twice daily for 4 days Result: Attenuated the attention deficit effectively. Prevented the learning and memory impairment in the spontaneous alternation and Morris water maze tests. significantly reduced lesion size microglia activation. |
| References |
| Molecular Formula | C20H23ClN2O2 |
|---|---|
| Molecular Weight | 358.862 |
| Exact Mass | 358.144806 |
| (3α,16α)-Eburnamenine-14-carboxylic acid hydrochloride (1:1) |
| Eburnamenine-14-carboxylic acid, (3α,16α)-, hydrochloride (1:1) |