2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine

Modify Date: 2025-08-26 19:21:14

2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine Structure
2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine structure
Common Name 2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine
CAS Number 722515-03-9 Molecular Weight 459.81
Density N/A Boiling Point N/A
Molecular Formula C18H17ClF3N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine


2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine

  Biological Activity

Description 2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C18H17ClF3N5O4
Molecular Weight 459.81
InChIKey BAZYLCHTDOGGPT-XNIJJKJLSA-N
SMILES OCC1OC(n2cnc3c(NCc4ccc(C(F)(F)F)cc4)nc(Cl)nc32)C(O)C1O
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