Thielavin A

Modify Date: 2024-01-02 09:17:49

Thielavin A Structure
Thielavin A structure
Common Name Thielavin A
CAS Number 71950-66-8 Molecular Weight 538.54200
Density 1.371g/cm3 Boiling Point 850ºC at 760 mmHg
Molecular Formula C29H30O10 Melting Point N/A
MSDS N/A Flash Point 281ºC

 Use of Thielavin A


Thielavin A is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin A specifically inhibits the conversion of arachidonic acid into prostaglandin H2. Thielavin A has no anti-inflammatory activity on intravenous injection or on oral administration[1].

 Names

Name 4-[4-(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,5,6-trimethylbenzoyl]oxy-2-hydroxy-3,5,6-trimethylbenzoic acid
Synonym More Synonyms

 Thielavin A Biological Activity

Description Thielavin A is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin A specifically inhibits the conversion of arachidonic acid into prostaglandin H2. Thielavin A has no anti-inflammatory activity on intravenous injection or on oral administration[1].
Related Catalog
References

[1]. Kitahara N, et al. Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot (Tokyo). 1981;34(12):1562-1568.

 Chemical & Physical Properties

Density 1.371g/cm3
Boiling Point 850ºC at 760 mmHg
Molecular Formula C29H30O10
Molecular Weight 538.54200
Flash Point 281ºC
Exact Mass 538.18400
PSA 170.82000
LogP 5.11280
Index of Refraction 1.646

 Synonyms

Thielavin A
4-({4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoyl}oxy)-2-hydroxy-3,5,6-trimethylbenzoic acid
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