Thielavin A

Names

[ CAS No. ]:
71950-66-8

[ Name ]:
Thielavin A

[Synonym ]:
Thielavin A
4-({4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoyl}oxy)-2-hydroxy-3,5,6-trimethylbenzoic acid

Biological Activity

[Description]:

Thielavin A is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin A specifically inhibits the conversion of arachidonic acid into prostaglandin H2. Thielavin A has no anti-inflammatory activity on intravenous injection or on oral administration[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[References]

[1]. Kitahara N, et al. Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot (Tokyo). 1981;34(12):1562-1568.

Chemical & Physical Properties

[ Density]:
1.371g/cm3

[ Boiling Point ]:
850ºC at 760 mmHg

[ Molecular Formula ]:
C₂₉H₃₀O₁₀

[ Molecular Weight ]:
538.54200

[ Flash Point ]:
281ºC

[ Exact Mass ]:
538.18400

[ PSA ]:
170.82000

[ LogP ]:
5.11280

[ Index of Refraction ]:
1.646

Related Compounds

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