3-Pyridinecarboxamide,2-amino-4,6-dimethyl-

Modify Date: 2024-01-12 12:12:24

3-Pyridinecarboxamide,2-amino-4,6-dimethyl- Structure
3-Pyridinecarboxamide,2-amino-4,6-dimethyl- structure
Common Name 3-Pyridinecarboxamide,2-amino-4,6-dimethyl-
CAS Number 7144-20-9 Molecular Weight 165.19200
Density 1.212 g/cm3 Boiling Point 268.3ºC at 760 mmHg
Molecular Formula C8H11N3O Melting Point 172-174 °C
MSDS N/A Flash Point 116.1ºC

 Names

Name 2-amino-4,6-dimethyl-3-pyridinecarboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.212 g/cm3
Boiling Point 268.3ºC at 760 mmHg
Melting Point 172-174 °C
Molecular Formula C8H11N3O
Molecular Weight 165.19200
Flash Point 116.1ºC
Exact Mass 165.09000
PSA 82.00000
LogP 1.66100
Storage condition 2-8°C

 MSDS

Name: 2-Amino-4 6-Dimethyl-3-Pyridinecarboxamide 93%(TLC) Material Safety Data Sheet
Synonym: None known
CAS: 7144-20-9
Section 1 - Chemical Product MSDS Name:2-Amino-4 6-Dimethyl-3-Pyridinecarboxamide 93%(TLC) Material Safety Data Sheet
Synonym:None known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
7144-20-9 2-Amino-4,6-Dimethyl-3-Pyridinecarboxa 93 unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.
Chronic:
Effects may be delayed.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 7144-20-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: beige
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 154 - 157 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C8H11N3O
Molecular Weight: 165.19

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 7144-20-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-Amino-4,6-Dimethyl-3-Pyridinecarboxamide - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 37/39 Wear suitable gloves and eye/face
protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 7144-20-9: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 7144-20-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 7144-20-9 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S37/39-S26
HS Code 2933399090

 Synthetic Route

~92%

3-Pyridinecarboxamide,2-amino-4,6-dimethyl- Structure

3-Pyridinecarbo...

CAS#:7144-20-9

Literature: Senanayake, Chris H.; Fredenburgh, Laura E.; Reamer, Robert A.; Liu, Ji; Larsen, Robert D.; Verhoeven, Thomas R.; Reider, Paul J. Tetrahedron Letters, 1994 , vol. 35, # 32 p. 5775 - 5778

~%

3-Pyridinecarboxamide,2-amino-4,6-dimethyl- Structure

3-Pyridinecarbo...

CAS#:7144-20-9

Literature: Journal of the American Chemical Society, , vol. 81, p. 2448,2451

~%

3-Pyridinecarboxamide,2-amino-4,6-dimethyl- Structure

3-Pyridinecarbo...

CAS#:7144-20-9

Literature: Journal of the American Chemical Society, , vol. 81, p. 2448,2451

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

MFCD00138572
2-amino-4,6-dimethylpyridine-3-carboxamide