![]() maysin structure
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Common Name | maysin | ||
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CAS Number | 70255-49-1 | Molecular Weight | 576.50300 | |
Density | 1.74g/cm3 | Boiling Point | 938.8ºC at 760 mmHg | |
Molecular Formula | C27H28O14 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 313.7ºC |
Use of maysinMaysin, a neuroprotective C-glycosyl-flavone, can be isolated from corn silk. Maysinshows protective activity against the damage caused by Syn amyloid aggregates-oligomers and fibrils. Maysinprevents oxidative stress and imbalance of intracellular calcium homeostasis, activating an autophagic degradative process. Maysincan be used for research of Parkinson's disease (PD)[1]. |
Name | maysin |
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Synonym | More Synonyms |
Description | Maysin, a neuroprotective C-glycosyl-flavone, can be isolated from corn silk. Maysinshows protective activity against the damage caused by Syn amyloid aggregates-oligomers and fibrils. Maysinprevents oxidative stress and imbalance of intracellular calcium homeostasis, activating an autophagic degradative process. Maysincan be used for research of Parkinson's disease (PD)[1]. |
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Related Catalog | |
In Vitro | Maysin (2.5-15 μM;24 小时) 在 2.5 μM 和 5 μM 时对 SH-SY5Y 细胞显示出不显着的细胞毒性[1]。 Maysin (2.5-15 μM;4 小时) 在 SH-SY5Y 细胞中通过自噬激活防止 Syn 寡聚体的细胞毒性[1]。 |
In Vivo | Maysin (100 mg/kg 玉米须提取物,高 Maysin 含量;口服;每天一次,持续 4 周) 对大鼠没有毒性[2]。 Maysin (100 mg/kg 玉米须提取物;口服;每天一次,持续 4 周) 抑制 5α-R2 和 PCNA 的 mRNA 表达,降低 5α-R2、DHT 和 PSA 的浓度,改善良性前列腺增生 (BPH) 大鼠模型[2]。 |
References |
Density | 1.74g/cm3 |
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Boiling Point | 938.8ºC at 760 mmHg |
Molecular Formula | C27H28O14 |
Molecular Weight | 576.50300 |
Flash Point | 313.7ºC |
Exact Mass | 576.14800 |
PSA | 236.81000 |
Index of Refraction | 1.745 |
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[4-hydroxy-6-methyl-5-oxo-3-(3,4,5-trihydroxy-6-methyl-oxan-2-yl)oxy-oxan-2-yl]chromen-4-one |
Maysin |
2,6-anhydro-1-deoxy-5-o-(6-deoxyhexopyranosyl)-6-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-6-yl]hex-3-ulose |
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[4-hydroxy-6-methyl-5-oxo-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]chromen-4-one |