maysin

Modify Date: 2025-08-24 18:53:45

maysin Structure
maysin structure
Common Name maysin
CAS Number 70255-49-1 Molecular Weight 576.50300
Density 1.74g/cm3 Boiling Point 938.8ºC at 760 mmHg
Molecular Formula C27H28O14 Melting Point N/A
MSDS N/A Flash Point 313.7ºC

 Use of maysin


Maysin, a neuroprotective C-glycosyl-flavone, can be isolated from corn silk. Maysinshows protective activity against the damage caused by Syn amyloid aggregates-oligomers and fibrils. Maysinprevents oxidative stress and imbalance of intracellular calcium homeostasis, activating an autophagic degradative process. Maysincan be used for research of Parkinson's disease (PD)[1].

 Names

Name maysin
Synonym More Synonyms

 maysin Biological Activity

Description Maysin, a neuroprotective C-glycosyl-flavone, can be isolated from corn silk. Maysinshows protective activity against the damage caused by Syn amyloid aggregates-oligomers and fibrils. Maysinprevents oxidative stress and imbalance of intracellular calcium homeostasis, activating an autophagic degradative process. Maysincan be used for research of Parkinson's disease (PD)[1].
Related Catalog
In Vitro Maysin (2.5-15 μM;24 小时) 在 2.5 μM 和 5 μM 时对 SH-SY5Y 细胞显示出不显着的细胞毒性[1]。 Maysin (2.5-15 μM;4 小时) 在 SH-SY5Y 细胞中通过自噬激活防止 Syn 寡聚体的细胞毒性[1]。
In Vivo Maysin (100 mg/kg 玉米须提取物,高 Maysin 含量;口服;每天一次,持续 4 周) 对大鼠没有毒性[2]。 Maysin (100 mg/kg 玉米须提取物;口服;每天一次,持续 4 周) 抑制 5α-R2 和 PCNA 的 mRNA 表达,降低 5α-R2、DHT 和 PSA 的浓度,改善良性前列腺增生 (BPH) 大鼠模型[2]。
References

[1]. Leri M, et al. Maysin plays a protective role against α-Synuclein oligomers cytotoxicity by triggering autophagy activation. Food Chem Toxicol. 2020 Oct;144:111626.  

[2]. Kim SR, et al. Corn silk extract improves benign prostatic hyperplasia in experimental rat model. Nutr Res Pract. 2017 Oct;11(5):373-380.  

 Chemical & Physical Properties

Density 1.74g/cm3
Boiling Point 938.8ºC at 760 mmHg
Molecular Formula C27H28O14
Molecular Weight 576.50300
Flash Point 313.7ºC
Exact Mass 576.14800
PSA 236.81000
Index of Refraction 1.745

 Synonyms

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[4-hydroxy-6-methyl-5-oxo-3-(3,4,5-trihydroxy-6-methyl-oxan-2-yl)oxy-oxan-2-yl]chromen-4-one
Maysin
2,6-anhydro-1-deoxy-5-o-(6-deoxyhexopyranosyl)-6-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-6-yl]hex-3-ulose
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[4-hydroxy-6-methyl-5-oxo-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]chromen-4-one
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