Neoisoliquiritigenin

Modify Date: 2025-08-22 12:46:41

Neoisoliquiritigenin Structure
Neoisoliquiritigenin structure
Common Name Neoisoliquiritigenin
CAS Number 7014-39-3 Molecular Weight 418.394
Density 1.528 Boiling Point 743.5±60.0 °C at 760 mmHg
Molecular Formula C21H22O9 Melting Point 230-232℃
MSDS N/A Flash Point 263.3±26.4 °C

 Use of Neoisoliquiritigenin


Neoisoliquiritigenin, isolated from Spatholobus suberectus, inhibits cell proliferation and induced cell apoptosis in breast cancer by directly binding to GRP78 to regulate the β-catenin pathway[1][2].

 Names

Name Neoisoliquiritin
Synonym More Synonyms

 Neoisoliquiritigenin Biological Activity

Description Neoisoliquiritigenin, isolated from Spatholobus suberectus, inhibits cell proliferation and induced cell apoptosis in breast cancer by directly binding to GRP78 to regulate the β-catenin pathway[1][2].
Related Catalog
References

[1]. Tang H, et al. Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer.Curr Cancer Drug Targets. 2018;18(4):390-399.

 Chemical & Physical Properties

Density 1.528
Boiling Point 743.5±60.0 °C at 760 mmHg
Melting Point 230-232℃
Molecular Formula C21H22O9
Molecular Weight 418.394
Flash Point 263.3±26.4 °C
Exact Mass 418.126373
LogP 0.76
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.707

 Synonyms

2Y348H1V4W
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)-
isoliquiritin
MFCD00272145
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-(β-D-glucopyranosyloxy)phenyl)-, (2E)-
4-[(1E)-3-(2,4-Dihydroxyphenyl)-3-oxo-1-propen-1-yl]phenyl β-D-glucopyranoside
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