7014-39-3

7014-39-3 structure

Name: Neoisoliquiritigenin
Chemical Name: Neoisoliquiritin
CAS Number: 7014-39-3
Molecular Formula: C₂₁H₂₂O₉
Molecular Weight: 418.394
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-10-15 22:15:05
Modify Date: 2025-08-22 12:46:41
Neoisoliquiritigenin, isolated from Spatholobus suberectus, inhibits cell proliferation and induced cell apoptosis in breast cancer by directly binding to GRP78 to regulate the β-catenin pathway[1][2].

Name	Neoisoliquiritin
Synonyms	2Y348H1V4W 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)- isoliquiritin MFCD00272145 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-(β-D-glucopyranosyloxy)phenyl)-, (2E)- 4-[(1E)-3-(2,4-Dihydroxyphenyl)-3-oxo-1-propen-1-yl]phenyl β-D-glucopyranoside

Description	Neoisoliquiritigenin, isolated from Spatholobus suberectus, inhibits cell proliferation and induced cell apoptosis in breast cancer by directly binding to GRP78 to regulate the β-catenin pathway[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Tang H, et al. Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer.Curr Cancer Drug Targets. 2018;18(4):390-399.