N-Boc-DL-serine methyl ester

Modify Date: 2025-08-24 20:55:40

N-Boc-DL-serine methyl ester structure	Common Name	N-Boc-DL-serine methyl ester
	CAS Number	69942-12-7	Molecular Weight	219.235
	Density	1.1±0.1 g/cm3	Boiling Point	354.3±32.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₇NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	168.1±25.1 °C

Use of N-Boc-DL-serine methyl ester

N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity[1][2][3].

Name	Methyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate
Synonym	More Synonyms

Description	N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Yang Yongqing, et al. Method for synthesizing α,β-dehydro-α-amino acid. Patent CN105037210. [2]. Wu Chengde, et al. Preparation of quinazolinone derivatives useful as PI3Kα inhibitors for the treatment of cancer. Patent WO2019091476. [3]. Pastor Fernandez, et al. Preparation of tricyclic pyrolopyranopyridines as protein kinase inhibitors. Patent WO2017033019.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Yang Yongqing, et al. Method for synthesizing α,β-dehydro-α-amino acid. Patent CN105037210.

[2]. Wu Chengde, et al. Preparation of quinazolinone derivatives useful as PI3Kα inhibitors for the treatment of cancer. Patent WO2019091476.

[3]. Pastor Fernandez, et al. Preparation of tricyclic pyrolopyranopyridines as protein kinase inhibitors. Patent WO2017033019.

Density	1.1±0.1 g/cm3
Boiling Point	354.3±32.0 °C at 760 mmHg
Molecular Formula	C₉H₁₇NO₅
Molecular Weight	219.235
Flash Point	168.1±25.1 °C
Exact Mass	219.110672
PSA	88.35000
LogP	0.80
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.461
Storage condition	2-8°C

Hazard Codes	Xi

Precursor 9
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DownStream 2
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