Swertisin

Modify Date: 2025-08-20 22:31:54

Swertisin structure	Common Name	Swertisin
	CAS Number	6991-10-2	Molecular Weight	462.404
	Density	1.6±0.1 g/cm3	Boiling Point	798.1±60.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₂O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	279.7±26.4 °C

Use of Swertisin

Swertisin, a C-glucosylflavone isolated from Swertia japonica, is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist[1][2].

Name	apigenin 6-glucosyl-7-o-methyl ether
Synonym	More Synonyms

Description	Swertisin, a C-glucosylflavone isolated from Swertia japonica, is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
References	[1]. Oh HK, et al. Swertisin ameliorates pre-pulse inhibition deficits and cognitive impairment induced by MK-801 in mice. J Psychopharmacol. 2017 Feb;31(2):250-259. [2]. Lee HE, et al. Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property. Behav Brain Res. 2016 Jun 1;306:137-45.

Description

Swertisin, a C-glucosylflavone isolated from Swertia japonica, is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist[1][2].

Related Catalog

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

References

[1]. Oh HK, et al. Swertisin ameliorates pre-pulse inhibition deficits and cognitive impairment induced by MK-801 in mice. J Psychopharmacol. 2017 Feb;31(2):250-259.

[2]. Lee HE, et al. Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property. Behav Brain Res. 2016 Jun 1;306:137-45.

Density	1.6±0.1 g/cm3
Boiling Point	798.1±60.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₂O₁₁
Molecular Weight	462.404
Flash Point	279.7±26.4 °C
Exact Mass	462.116211
PSA	179.28000
LogP	-1.03
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.695