2'-O-t-Butyldimethylsilyl adenosine

Modify Date: 2025-08-25 11:06:34

2'-O-t-Butyldimethylsilyl adenosine structure	Common Name	2'-O-t-Butyldimethylsilyl adenosine
	CAS Number	69504-13-8	Molecular Weight	381.50200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₇N₅O₄Si	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2'-O-t-Butyldimethylsilyl adenosine

2’-O-t-Butyldimethylsilyladenosine is a adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Name	(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[tert-butyl(dimethyl)silyl]oxy-2-(hydroxymethyl)oxolan-3-ol
Synonym	More Synonyms

Description	2’-O-t-Butyldimethylsilyladenosine is a adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Molecular Formula	C₁₆H₂₇N₅O₄Si
Molecular Weight	381.50200
Exact Mass	381.18300
PSA	128.54000
LogP	1.63070
InChIKey	UYYHTFUFYVROBD-SDBHATRESA-N
SMILES	CC(C)(C)[Si](C)(C)OC1C(O)C(CO)OC1n1cnc2c(N)ncnc21