Lappaol F

Modify Date: 2025-08-25 14:37:19

Lappaol F Structure
Lappaol F structure
Common Name Lappaol F
CAS Number 69394-17-8 Molecular Weight 714.75
Density N/A Boiling Point N/A
Molecular Formula C40H42O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lappaol F


Lappaol F, a lignin, is an anticancer agent. Lappaol F inhibits YAP<、b> mRNA and protein level. Lappaol F inhibits tumor cell growth by inducing cell cycle arrest. Lappaol F induces cancer cell apoptosis, and inhibits tumor growth. Lappaol F can be isolated from Arctium lappa Linne (Asteraceae)[1].

 Names

Name Lappaol F
Synonym More Synonyms

 Lappaol F Biological Activity

Description Lappaol F, a lignin, is an anticancer agent. Lappaol F inhibits YAP<、b> mRNA and protein level. Lappaol F inhibits tumor cell growth by inducing cell cycle arrest. Lappaol F induces cancer cell apoptosis, and inhibits tumor growth. Lappaol F can be isolated from Arctium lappa Linne (Asteraceae)[1].
Related Catalog
References

[1]. Li X, et al. Lappaol F, an anticancer agent, inhibits YAP via transcriptional and post-translational regulation. Pharm Biol. 2021 Dec;59(1):619-628.  

[2]. Sun Q, et al. Lappaol F, a novel anticancer agent isolated from plant arctium Lappa L. Mol Cancer Ther. 2014 Jan;13(1):49-59.  

 Chemical & Physical Properties

Molecular Formula C40H42O12
Molecular Weight 714.75
InChIKey YXNKOCZXAVTXTG-NYGVLQSXSA-N
SMILES COc1cc(C2Oc3c(OC)cc(CC4COC(=O)C4Cc4cc(OC)c5c(c4)C(CO)C(c4ccc(O)c(OC)c4)O5)cc3C2CO)ccc1O

 Synonyms

2(3H)-Furanone, 3,4-bis[[(2S,3R)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-5-benzofuranyl]methyl]dihydro-, (3R,4R)-
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