69394-17-8

69394-17-8 structure

Name: Lappaol F
Chemical Name: Lappaol F
CAS Number: 69394-17-8
Molecular Formula: C₄₀H₄₂O₁₂
Molecular Weight: 714.75
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-02-24 19:59:29
Modify Date: 2023-02-24 19:59:29
Lappaol F, a lignin, is an anticancer agent. Lappaol F inhibits YAP<、b> mRNA and protein level. Lappaol F inhibits tumor cell growth by inducing cell cycle arrest. Lappaol F induces cancer cell apoptosis, and inhibits tumor growth. Lappaol F can be isolated from Arctium lappa Linne (Asteraceae)[1].

Name	Lappaol F
Synonyms	2(3H)-Furanone, 3,4-bis[[(2S,3R)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-5-benzofuranyl]methyl]dihydro-, (3R,4R)-

Description	Lappaol F, a lignin, is an anticancer agent. Lappaol F inhibits YAP<、b> mRNA and protein level. Lappaol F inhibits tumor cell growth by inducing cell cycle arrest. Lappaol F induces cancer cell apoptosis, and inhibits tumor growth. Lappaol F can be isolated from Arctium lappa Linne (Asteraceae)[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> YAP
References	[1]. Li X, et al. Lappaol F, an anticancer agent, inhibits YAP via transcriptional and post-translational regulation. Pharm Biol. 2021 Dec;59(1):619-628. [2]. Sun Q, et al. Lappaol F, a novel anticancer agent isolated from plant arctium Lappa L. Mol Cancer Ther. 2014 Jan;13(1):49-59.

Molecular Formula	C₄₀H₄₂O₁₂
Molecular Weight	714.75