3'-Deoxyuridine-5'-triphosphate
Modify Date: 2024-01-21 14:35:15
3'-Deoxyuridine-5'-triphosphate structure
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Common Name | 3'-Deoxyuridine-5'-triphosphate | ||
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| CAS Number | 69199-40-2 | Molecular Weight | 468.14200 | |
| Density | 2.01g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H15N2O14P3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3'-Deoxyuridine-5'-triphosphate3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. |
| Name | [[(2S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate |
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| Synonym | More Synonyms |
| Description | 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. |
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| Related Catalog | |
| In Vitro | 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-triphosphate will be useful in studies at the molecular level on the relationship of template and substrate in RNA synthesis with chromatin, isolated nuclei or permeable cells, because it does not have any effect on poly (rA) synthesis[1]. |
| References |
| Density | 2.01g/cm3 |
|---|---|
| Molecular Formula | C9H15N2O14P3 |
| Molecular Weight | 468.14200 |
| Exact Mass | 467.97400 |
| PSA | 273.83000 |
| Index of Refraction | 1.618 |
| 3'-deoxy-UTP |
| 3'-Deoxyuridine-5'-triphosphate |
| 3'-Deoxyuridin-5'-triphosphat |
| 3'-dUTP |