Carbazochrome
Modify Date: 2024-01-04 11:50:39
Carbazochrome structure
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Common Name | Carbazochrome | ||
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| CAS Number | 69-81-8 | Molecular Weight | 236.227 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C10H12N4O3 | Melting Point | 203° (dec) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of CarbazochromeCarbazochrome is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome is an antihemorrhagic agent[1]. |
| Name | Carbazochrome |
|---|---|
| Synonym | More Synonyms |
| Description | Carbazochrome is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome is an antihemorrhagic agent[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Carbazochrome (0.1-10 µM) inhibits the Bradykinin induced and thrombin-induced formation of [3H]IP3 in a concentration-dependent manner[1].Carbazochrome (0.1-1 µM), when included from 30 min before stimulation, significantly suppressed the enhancement of permeability induced by vasoactive substances[1]. |
| In Vivo | Carbazochrome inhibits the severe pulmonary dysfunction induced by the intravenous injection of radiographic contrast media. Carbazochrome (1-10 mg/kg, i.v.) attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats[2]. Animal Model: Male Sprague-Dawley rats weighing 180-230 g[2] Dosage: 10 mg/kg Administration: I.v.; injected 30, 60, or 90 min before Ioxaglate injection (4 g I/kg, i.v.). Result: Attenuated the Ioxaglate-increased vascular permeability at the dose of 1, 5 and 10 mg/kg in a dose-dependent manner, achieving statistical significance at 5 and 10 mg/kg. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Melting Point | 203° (dec) |
| Molecular Formula | C10H12N4O3 |
| Molecular Weight | 236.227 |
| Exact Mass | 236.090942 |
| PSA | 108.02000 |
| LogP | -1.53 |
| Index of Refraction | 1.733 |
| Storage condition | −20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Carbazochrome CAS#:69-81-8 |
| Literature: Zhurnal Obshchei Khimii, , vol. 28, p. 3338,3341,3344;engl.Ausg.S.3364,3367 |
| Precursor 1 | |
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| DownStream 0 | |
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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[Host-guest molecule interaction mechanism of hemostatics with liposomes and red blood cells studied with fluorescence polarimetric method].
Yao Xue Xue Bao 33(5) , 362-8, (1998) The supermolecule compounds of adrenobazone, p-aminomethylbenzoic acid, vitamin K1, 6-amino caproic acid with liposomes and red blood cells were studied by fluorescence polarimetric method. The mechan... |
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Parenteral troxerutin and carbazochrome combination in the treatment of post-hemorrhoidectomy status: a randomized, double-blind, placebo-controlled, phase IV study.
Curr. Med. Res. Opin. 17(4) , 256-61, (2001) Flavonoids, such as troxerutin, have been shown to be safe and effective agents for the treatment of chronic venous insufficiency. The fixed combination between troxerutin 150 mg and carbazochrome 1.5... |
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Short-term delayed-release microcapsules spraycoated with acrylic terpolymers.
Int. J. Pharm. 307(2) , 300-7, (2006) A series of poly(ethyl acrylate (EA)/methyl methacrylate (MMA)/2-hydroxyethyl methacrylate (HEMA)) lattices were synthesized to prepare short-term delayed-release microcapsules by employing the Wurste... |
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