Econazole nitrate

Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Cold water may be used. WARM water MUST be used. Get medical attention if irritation
occurs.
Skin ContactIn case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient.
Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before
reuse. Get medical attention.
Serious Skin Contact
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Serious InhalationNot available.
IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen
tight clothing such as a collar, tie, belt or waistband.
Serious IngestionNot available.

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Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Not available.
Flash Points
Flammable LimitsNot available.
Products of CombustionThese products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks onMaterial in powder form, capable of creating a dust explosion.
Fire Hazards
Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential
dust explosion hazard.
Hazards

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Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
Econazole nitrate

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Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
ingest. Do not breathe dust. Avoid contact with skin. Wear suitable protective clothing. If ingested, seek
medical advice immediately and show the container or the label.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in
light-resistant containers.

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Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
exposure to airborne contaminants below the exposure limit.
Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
a Large Spillused to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product.
Exposure LimitsNot available.

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Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (crystalline powder.)Not available.
Odor
TasteNot available.
Molecular Weight440.7 g/mole
ColorWhite. Off-white.
pH (1% soln/water)Not available.
Boiling PointNot available.
Melting Point162°C (323.6°F)
Critical TemperatureNot available.
Not available.
Specific Gravity
Vapor PressureNot applicable.
Not available.
Vapor Density
VolatilityNot available.
Odor ThresholdNot available.
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
See solubility in water, methanol.
Dispersion Properties
SolubilitySoluble in methanol.
Very slightly soluble in cold water.

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Section 10. Stability and Reactivity Data
The product is stable.
Stability
Instability TemperatureNot available.
Excess heat, dust generation
Conditions of Instability
Incompatibility with variousNot available.
substances
CorrosivityNon-corrosive in presence of glass.
Special Remarks onSensitive to light.
Reactivity
Econazole nitrate
Not available.
Special Remarks on
Corrosivity
PolymerizationWill not occur.

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Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
Toxicity to AnimalsAcute oral toxicity (LD50): 431 mg/kg [Rabbit].
Chronic Effects on Humans Not available.
Other Toxic Effects onHazardous in case of skin contact (irritant).
HumansSlightly hazardous in case of ingestion, of inhalation.
Special Remarks onNot available.
Toxicity to Animals
Special Remarks onMay affect genetic material (mutagenic).
Chronic Effects on HumansMay cause adverse reproductive effects and birth defects (teratogenic) based on animal test data
Special Remarks on otherAcute Potential Health Effects:
Toxic Effects on HumansSkin: Can cause skin irritation.
Eyes: Can cause eye irritation.
Inhalation: May cause respiratory tract irritation.
Ingestion: May be harmful if swallowed. May affect behavior/central nervous system (tremor, convulsions),
respiration (dyspnea), liver, blood (changes in serum composition)

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Section 12. Ecological Information
EcotoxicityNot available.
BOD5 and CODNot available.
Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products
may arise.
Toxicity of the ProductsThe products of degradation are as toxic as the product itself.
of Biodegradation
Special Remarks on theNot available.
Products of Biodegradation

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Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.

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Section 14. Transport Information
DOT ClassificationNot a DOT controlled material (United States).
Not applicable.
Identification
Special Provisions forNot applicable.
Transport
DOT (Pictograms)
Econazole nitrate

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Section 15. Other Regulatory Information and Pictograms
New Jersey: Econazole nitrate
Federal and State
Regulations
CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has
Proposition 65found to cause cancer which would require a warning under the statute: No products were found.
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has
found to cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS
No. 272-295-6).
Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non-Domestic Substances List
(NDSL)
China: Not listed on National Inventory.
Japan: Not listed on National Inventory (ENCS).
Korea: Listed on National Inventory (KECI).
Philippines: Not listed on National Inventory (PICCS).
Australia: Listed on AICS.
WHMIS (Canada) CLASS D-2B: Material causing other toxic effects (TOXIC).
Other Classifications
DSCL (EEC)R22- Harmful if swallowed.S26- In case of contact with eyes, rinse
R36/38- Irritating to eyes and skin.immediately with plenty of water and seek
medical advice.
S37- Wear suitable gloves.
S46- If swallowed, seek medical advice
immediately and show this container or label.
Health Hazard
HMIS (U.S.A.)1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Econazole nitrate
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate
respirator when ventilation is
inadequate.

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SECTION 16 - ADDITIONAL INFORMATION
N/A