Dehydroeburicoic acid

Modify Date: 2024-01-09 10:48:52

Dehydroeburicoic acid Structure
Dehydroeburicoic acid structure
Common Name Dehydroeburicoic acid
CAS Number 6879-05-6 Molecular Weight 468.71100
Density 1.07±0.1 g/cm3 Boiling Point N/A
Molecular Formula C31H48O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dehydroeburicoic acid


Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects[1].

 Names

Name Dehydroeburicoic acid
Synonym More Synonyms

 Dehydroeburicoic acid Biological Activity

Description Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects[1].
Related Catalog
Target

Caspase-3

In Vivo Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed cells with a GI50 value of 40 μM[1].
References

[1]. Kang HM, et al. Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway. Life Sci. 2006 Jan 2;78(6):607-13.

 Chemical & Physical Properties

Density 1.07±0.1 g/cm3
Molecular Formula C31H48O3
Molecular Weight 468.71100
Exact Mass 468.36000
PSA 57.53000
LogP 7.56580
Water Solubility Insuluble (6.1E-6 g/L) (25 ºC)

 Synonyms

(R)-2-((3S,5R,10S,13R,14R,17R)-3-Hydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methyl-5-methylene-heptanoic acid
3β-Hydroxy-eburica-7,9(11),24(28)-trien-21-saeure
dehydroeburicoic acid
3β-Hydroxy-24-methylen-lanosta-7,9(11)-dien-21-saeure
3β-hydroxy-eburica-7,9(11),24(28)-trien-21-oic acid