6879-05-6

6879-05-6 structure

Name: Dehydroeburicoic acid
Chemical Name: Dehydroeburicoic acid
CAS Number: 6879-05-6
Molecular Formula: C₃₁H₄₈O₃
Molecular Weight: 468.71100
Catalog: Signaling Pathways Apoptosis Caspase
Create Date: 2018-09-08 23:14:06
Modify Date: 2024-01-09 10:48:52
Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects[1].

Name	Dehydroeburicoic acid
Synonyms	(R)-2-((3S,5R,10S,13R,14R,17R)-3-Hydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methyl-5-methylene-heptanoic acid 3β-Hydroxy-eburica-7,9(11),24(28)-trien-21-saeure dehydroeburicoic acid 3β-Hydroxy-24-methylen-lanosta-7,9(11)-dien-21-saeure 3β-hydroxy-eburica-7,9(11),24(28)-trien-21-oic acid

Description	Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Inflammation/Immunology
Target	Caspase-3
In Vivo	Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed cells with a GI50 value of 40 μM[1].
References	[1]. Kang HM, et al. Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway. Life Sci. 2006 Jan 2;78(6):607-13.