Echitamine chloride

Modify Date: 2024-01-10 11:53:14

Echitamine chloride Structure
Echitamine chloride structure
Common Name Echitamine chloride
CAS Number 6878-36-0 Molecular Weight 385.47700
Density N/A Boiling Point N/A
Molecular Formula C22H29ClN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Echitamine chloride


Echitamine chloride is the major monoterpene indole alkaloid present in Alstonia with potent anti-tumour activity. Echitamine chloride induces DNA fragmentation and cells apoptosis. Echitamine chloride inhibits pancreatic lipase with an IC50 of 10.92 µM[1][2].

 Names

Name echetamine chloride

 Echitamine chloride Biological Activity

Description Echitamine chloride is the major monoterpene indole alkaloid present in Alstonia with potent anti-tumour activity. Echitamine chloride induces DNA fragmentation and cells apoptosis. Echitamine chloride inhibits pancreatic lipase with an IC50 of 10.92 µM[1][2].
Related Catalog
Target

IC50: 10.92 µM (Pancreatic lipase)[2]

References

[1]. Ganesh Chandra Jagetia, et al. Evaluation of the Cytotoxic Effect of the Monoterpene Indole Alkaloid Echitamine In-Vitro and in Tumour-Bearing Mice. J Pharm Pharmacol. 2005 Sep;57(9):1213-9.

[2]. Ginson George, et al. Development and Validation of a New HPTLC-HRMS Method for the Quantification of a Potent Pancreatic Lipase Inhibitory Lead Echitamine From Alstonia scholaris. Nat Prod Res. 2019 Dec 24;1-5.

 Chemical & Physical Properties

Molecular Formula C22H29ClN2O4
Molecular Weight 385.47700
Exact Mass 385.21300
PSA 78.79000
LogP 1.48570
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