3-(2-Pyridyldithio)propanoic Acid
3-(2-Pyridyldithio)propanoic Acid structure
|
Common Name | 3-(2-Pyridyldithio)propanoic Acid | ||
|---|---|---|---|---|
| CAS Number | 68617-64-1 | Molecular Weight | 215.29300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H9NO2S2 | Melting Point | 68-71C | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3-(2-Pyridyldithio)propanoic Acid3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 3-(pyridin-2-yldisulfanyl)propanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Melting Point | 68-71C |
|---|---|
| Molecular Formula | C8H9NO2S2 |
| Molecular Weight | 215.29300 |
| Exact Mass | 215.00700 |
| PSA | 100.79000 |
| LogP | 2.29660 |
| Storage condition | -20°C |
|
~98%
3-(2-Pyridyldit... CAS#:68617-64-1 |
| Literature: WO2005/112919 A2, ; Page/Page column 151 ; |
|
~10%
3-(2-Pyridyldit... CAS#:68617-64-1 |
| Literature: US5405966 A1, ; |
|
~74%
3-(2-Pyridyldit... CAS#:68617-64-1 |
| Literature: Synthetic Communications, , vol. 28, # 17 p. 3213 - 3217 |
|
~85%
3-(2-Pyridyldit... CAS#:68617-64-1
Detail
|
| Literature: Journal of the American Chemical Society, , vol. 120, # 46 p. 12108 - 12116 |
|
~%
3-(2-Pyridyldit... CAS#:68617-64-1 |
| Literature: US5630996 A1, ; |
|
~%
Detail
|
| Literature: US4340535 A1, ; |
|
~%
3-(2-Pyridyldit... CAS#:68617-64-1 |
| Literature: Synthetic Communications, , vol. 28, # 17 p. 3213 - 3217 |
|
~%
3-(2-Pyridyldit... CAS#:68617-64-1 |
| Literature: Journal of Medicinal Chemistry, , vol. 53, # 13 p. 4877 - 4890 |
CAS#:68181-17-9| 2-carboxyethyl-pyridin-2-yldisulphide |
| 3-(2-Pyridinyldithio)propanoic Acid |
| 3-(2-Pyridyldithio)propanoic acid |
| Propanoic acid,3-(2-pyridinyldithio) |
| 2-Carboxyethyl 2-Pyridyl Disulfide |
| 3-(PYRIDIN-2-YLDITHIO)PROPANOIC ACID |
| 3-(2-pyridinyldisulfanyl)propanoic acid |
| 3-(pyridin-2-yldithio)-propionic acid |
| 3-(2-Pyridyldithio)propionic acid |
| 3-(pyridin-2-yldisulfanyl)propionic acid |