JNK-IN-11

Modify Date: 2025-11-27 09:25:28

JNK-IN-11 structure	Common Name	JNK-IN-11
	CAS Number	676594-38-0	Molecular Weight	281.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₁NO₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JNK-IN-11

JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].

Name	JNK-IN-11

Description	JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> MAPK/ERK Pathway >> JNK
Target	JNK1:1.8 μM (IC50) JNK3:2.2 μM (IC50) JNK2:21.4 μM (IC50)
References	[1]. Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7303-7.

Molecular Formula	C₁₂H₁₁NO₃S₂
Molecular Weight	281.35
InChIKey	CXOCENPNQSXLGZ-UHFFFAOYSA-N
SMILES	COC(=O)c1sccc1NC(=O)Cc1cccs1

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