N-Butanoyl-L-homoserine lactone structure
|
Common Name | N-Butanoyl-L-homoserine lactone | ||
|---|---|---|---|---|
| CAS Number | 67605-85-0 | Molecular Weight | 171.194 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 428.1±34.0 °C at 760 mmHg | |
| Molecular Formula | C8H13NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 212.7±25.7 °C | |
Use of N-Butanoyl-L-homoserine lactoneN-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. |
| Name | N-[(3S)-2-oxooxolan-3-yl]butanamide |
|---|---|
| Synonym | More Synonyms |
| Description | N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 428.1±34.0 °C at 760 mmHg |
| Molecular Formula | C8H13NO3 |
| Molecular Weight | 171.194 |
| Flash Point | 212.7±25.7 °C |
| Exact Mass | 171.089539 |
| PSA | 55.40000 |
| LogP | -1.10 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.476 |
| Storage condition | 2-8°C |
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N-Butanoyl-L-ho... CAS#:67605-85-0 |
| Literature: Nippon Kagaku Zasshi, , vol. 79, p. 81,83 Chem.Abstr., , p. 5448 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| C4-homoserine lactone |
| Butanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]- |
| N-Butyryl-DL-homoserin-lacton |
| HL4 |
| N-Butyryl-L-homoserine lactone |
| N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide |
| (+)-a(S)-butyr-amido-r-butyrolactone |
| N-[(3S)-2-Oxotetrahydro-3-furanyl]butanamide |
| butanoyl homoserine lactone |