Catalposide

Modify Date: 2024-01-03 09:38:53

Catalposide structure	Common Name	Catalposide
	CAS Number	6736-85-2	Molecular Weight	482.435
	Density	1.7±0.1 g/cm3	Boiling Point	766.3±60.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₆O₁₂	Melting Point	215-216.5°
	MSDS	Chinese USA	Flash Point	266.7±26.4 °C

Use of Catalposide

Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages[1].

Name	catalpin
Synonym	More Synonyms

Description	Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages[1].
Related Catalog	Research Areas >> Inflammation/Immunology
In Vitro	Catalposide (1-1000 ng/mL) could inhibit TNF-a, IL-1β, and IL-6 productions in RAW 264.7 macrophages[1].
References	[1]. S J An, et al. Inhibition of TNF-alpha, IL-1beta, and IL-6 productions and NF-kappa B activation in lipopolysaccharide-activated RAW 264.7 macrophages by catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). Int Immunopharmacol. 2002 Jul;2(8):1173-81.

Density	1.7±0.1 g/cm3
Boiling Point	766.3±60.0 °C at 760 mmHg
Melting Point	215-216.5°
Molecular Formula	C₂₂H₂₆O₁₂
Molecular Weight	482.435
Flash Point	266.7±26.4 °C
Exact Mass	482.142426
PSA	187.90000
LogP	-2.18
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.696

Catalposide MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ5776783

CHEMICAL NAME :: beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-((4-hydroxybenzoyl)oxy)- 1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran- 2-yl, (1aS-(1a-alpha,1b-beta,2-beta,5a- beta,6-beta,6a-alpha))-

CAS REGISTRY NUMBER :: 6736-85-2

LAST UPDATED :: 199806

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H26-O12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 64,93,1968

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 64,93,1968

Hazard Codes	Xi
RIDADR	NONH for all modes of transport
HS Code	29389090

Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide.

J. Pharm. Biomed. Anal. 48(1) , 127-33, (2008)

The antioxidant properties of pomiferin, isopomiferin, osajin and catalposide are evaluated. The electrochemical behaviour of these compounds at a carbon paste electrode was studied using square wave ...

Hostplant suitability and defensive chemistry of the Catalpa sphinx, Ceratomia catalpae.

J. Chem. Ecol. 29(10) , 2359-67, (2003)

The growth and survival of the Catalpa sphinx, Ceratomia catalpae (Sphingidae), were measured on five different species of Catalpa: C. bignonioides, C. bungeii, C. fargeseii, C. ovata, and C. speciosa...

Inhibition of TNF-alpha, IL-1beta, and IL-6 productions and NF-kappa B activation in lipopolysaccharide-activated RAW 264.7 macrophages by catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae).

Int. Immunopharmacol. 2(8) , 1173-81, (2002)

Catalposide, the major iridoid glycoside isolated from the stem bark of Catalpa ovata G. Don (Bignoniaceae), was found to inhibit the productions of tumor necrosis factor-alpha (TNF-alpha), interleuki...

(1aS,1bS,2S,5aR,6S,6aS)-2-(β-D-Glucopyranosyloxy)-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxybenzoate

[1aS-(1aa,1bb,2b,5ab,6b,6aa)]-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-b-D-glucopyranoside

Einecs 229-789-1

hydroxybenzoylcatalpol

Benzoic acid, 4-hydroxy-, (1aS,1bS,2S,5aR,6S,6aS)-2-(β-D-glucopyranosyloxy)-1a,1b,2,5a,6,6a-hexahydro-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-6-yl ester

CATALPOSIDE