(Deamino-Pen1,Tyr(Me)2, Arg8)-Vasopressin trifluoroacetate salt

Modify Date: 2024-01-16 10:01:32

(Deamino-Pen1,Tyr(Me)2, Arg8)-Vasopressin trifluoroacetate salt structure	Common Name	(Deamino-Pen1,Tyr(Me)2, Arg8)-Vasopressin trifluoroacetate salt
	CAS Number	67269-08-3	Molecular Weight	1111.30
	Density	1.49g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₉H₇₀N₁₄O₁₂S₂	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of (Deamino-Pen1,Tyr(Me)2, Arg8)-Vasopressin trifluoroacetate salt

Dp[Tyr(methyl)2,Arg8]-Vasopressin is a non-selective peptide arginine vasopressin Vlb receptor antagonist[1].

Name	1-Deaminopenicillamine-2-(O-methyl-tyr)-argipressin
Synonym	More Synonyms

Description	Dp[Tyr(methyl)2,Arg8]-Vasopressin is a non-selective peptide arginine vasopressin Vlb receptor antagonist[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor Research Areas >> Metabolic Disease
References	[1]. Kamal A. Al-Barazanji. Use of vasopressin receptor antagonist for regulation of acth release. WO1997035602A1.

Density	1.49g/cm3
Molecular Formula	C₄₉H₇₀N₁₄O₁₂S₂
Molecular Weight	1111.30
Exact Mass	1110.47000
PSA	475.01000
LogP	2.60510
Index of Refraction	1.684

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H332
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
RIDADR	NONH for all modes of transport

Arginine vasopressin enhances pHi regulation in the presence of HCO3- by stimulating three acid-base transport systems.

Nature 337(6208) , 648-51, (1989)

Growth factors raise intracellular pH (pHi) by stimulating Na+/H+ exchange in the absence of HCO3-. In mutant cells that lack the Na+/H+ exchange activity, this alkalinization does not occur, and the ...

Arginine vasopressin in advanced vasodilatory shock: a prospective, randomized, controlled study.

Circulation 107(18) , 2313-9, (2003)

Vasodilatory shock is a potentially lethal complication of severe disease in critically ill patients. Currently, catecholamines are the most widely used vasopressor agents to support blood pressure, b...

Role of arginine vasopressin V1 and V2 receptors for brain damage after transient focal cerebral ischemia.

J. Cereb. Blood Flow Metab. 25(8) , 1012-9, (2005)

Brain edema formation is one of the most important mechanisms responsible for brain damage after ischemic stroke. Despite considerable efforts, no specific therapy is available yet. Arginine vasopress...

vasopressin deamino-Pen1,O-Me-tyrosine-2,arginine-8

(DEAMINO-PEN1,TYR(ME)2,ARG8)-VASOPRESSIN

3-mercapto-3-methyl-butyryl-tyr(me)-phe-gln-asn-cys-pro-arg-gly-nh2

[Pmp1,Tyr(OMe)2,Arg8] Vasopressin