Cinobufaginol

Modify Date: 2024-01-06 00:57:04

Cinobufaginol Structure
Cinobufaginol structure
Common Name Cinobufaginol
CAS Number 6691-83-4 Molecular Weight 458.54400
Density N/A Boiling Point N/A
Molecular Formula C26H34O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cinobufaginol


Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively[1].

 Names

Name Cinobufaginol
Synonym More Synonyms

 Cinobufaginol Biological Activity

Description Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively[1].
Related Catalog
References

[1]. Liu JS, et al. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolidesfrom toad venom. Fitoterapia. 2019 Apr;134:362-371.

 Chemical & Physical Properties

Molecular Formula C26H34O7
Molecular Weight 458.54400
Exact Mass 458.23000
PSA 109.50000
LogP 2.77230

 Safety Information

Hazard Codes Xi

 Synonyms

5beta-Bufa-20,22-dienolide,14,15beta-epoxy-3beta,16beta,19-trihydroxy-,16-acetate
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