2-Chloro-6-methoxybenzonitrile

Modify Date: 2024-01-02 09:07:02

2-Chloro-6-methoxybenzonitrile Structure
2-Chloro-6-methoxybenzonitrile structure
Common Name 2-Chloro-6-methoxybenzonitrile
CAS Number 6575-10-6 Molecular Weight 167.592
Density 1.3±0.1 g/cm3 Boiling Point 294.7±20.0 °C at 760 mmHg
Molecular Formula C8H6ClNO Melting Point 98-100ºC
MSDS USA Flash Point 132.0±21.8 °C

 Names

Name 2-Chloro-6-methoxybenzonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 294.7±20.0 °C at 760 mmHg
Melting Point 98-100ºC
Molecular Formula C8H6ClNO
Molecular Weight 167.592
Flash Point 132.0±21.8 °C
Exact Mass 167.013794
PSA 33.02000
LogP 2.66
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.549
Storage condition 2-8°C

 MSDS

Name: 2-Chloro-6-methoxybenzonitrile 97% Material Safety Data Sheet
Synonym:
CAS: 6575-10-6
Section 1 - Chemical Product MSDS Name:2-Chloro-6-methoxybenzonitrile 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
6575-10-6 2-Chloro-6-methoxybenzonitrile, 97% 97 229-500-9
Hazard Symbols: XN
Risk Phrases: 20/21/22

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Appearance: very slightly beige needle like crystalline Target Organs: None.
Potential Health Effects
The toxicological properties of this material have not been investigated. Use appropriate procedures to prevent opportunities for direct contact with the skin or eyes and to prevent inhalation.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Sweep up, then place into a suitable container for disposal.

Section 7 - HANDLING and STORAGE
Handling:
Not available.
Storage:
Not available.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits +--------------------+-------------------+-------------------+-----------------+ | Chemical Name | ACGIH | NIOSH |OSHA - Final PELs| |--------------------|-------------------|-------------------|-----------------| | 2-Chloro-6-methoxyb|none listed |none listed |none listed | | enzonitrile, 97% | | | | +--------------------+-------------------+-------------------+-----------------+ OSHA Vacated PELs: 2-Chloro-6-methoxybenzonitrile, 97%: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment Eyes: Wear safety glasses and chemical goggles if splashing is possible.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Not available.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Not available.
Appearance: very slightly beige
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 113.00 - 115.00 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Explosion Limits, Lower: Not available.
Upper: Not available.
Decomposition Temperature:
Solubility:
Specific Gravity/Density:
Molecular Formula: C8H6ClNO
Molecular Weight: 167.59

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Not available.
Incompatibilities with Other Materials:
Not available.
Hazardous Decomposition Products:
Not available.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 6575-10-6 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-Chloro-6-methoxybenzonitrile, 97% - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Chemical waste generators must determine whether a discarded chemical is classif as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Part Additionally, waste generators must consult state and local hazardous waste regu ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - TRANSPORT INFORMATION

CDG/CPL
Not classified as hazardous for supply.
Canadian TDG
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 6575-10-6: No information available.
United Kingdom Occupational Exposure Limits
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
WHMIS: Not available.
CAS# 6575-10-6 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 6575-10-6 is not listed on the TSCA inventory.
It is for research and development use only.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
HS Code 2926909090

 Synthetic Route

~57%

2-Chloro-6-methoxybenzonitrile Structure

2-Chloro-6-meth...

CAS#:6575-10-6

Literature: SmithKline Beecham Corporation Patent: US6294531 B1, 2001 ;

~%

2-Chloro-6-methoxybenzonitrile Structure

2-Chloro-6-meth...

CAS#:6575-10-6

Literature: Journal of the Chemical Society, , p. 192 Journal of the Chemical Society, , p. 2918,2923

~%

2-Chloro-6-methoxybenzonitrile Structure

2-Chloro-6-meth...

CAS#:6575-10-6

Literature: Journal of the Chemical Society, , p. 192 Journal of the Chemical Society, , p. 2918,2923

 Customs

HS Code 2926909090
Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

2-Chloro-6-methoxybenzonitrile
Benzonitrile, 2-chloro-6-methoxy-