Ophiopogonin D'

Modify Date: 2025-08-25 17:52:18

Ophiopogonin D' structure	Common Name	Ophiopogonin D'
	CAS Number	65604-80-0	Molecular Weight	855.017
	Density	1.4±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₄H₇₀O₁₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ophiopogonin D'

Ophiopogonin D', isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D' shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC50s of 3.09 μM and 3.63 μM, respectively[1]. Ophiopogonin D' activates SIRT1 in a dose-dependent manner[2].

Name	(3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-β-D-glucopyranoside
Synonym	More Synonyms

Description	Ophiopogonin D', isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D' shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC50s of 3.09 μM and 3.63 μM, respectively[1]. Ophiopogonin D' activates SIRT1 in a dose-dependent manner[2].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin
Target	SIRT1
References	[1]. Wang L , et al. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogonjaponicus. Phytochemistry. 2017 Apr;136:125-132. [2]. Wang Y, et al. Specific Turn-On Fluorescent Probe with Aggregation-Induced EmissionCharacteristics for SIRT1 Modulator Screening and Living-Cell Imaging. Anal Chem. 2015;87(10):5046-9.

Density	1.4±0.1 g/cm3
Molecular Formula	C₄₄H₇₀O₁₆
Molecular Weight	855.017
Exact Mass	854.466370
PSA	235.68000
LogP	6.69
Index of Refraction	1.618
Storage condition	2-8°C

Precursor 0
DownStream 6
CAS#:87-72-9 L-Arabinopyranose CAS#:2280-44-6 D-glucopyranose CAS#:470-05-3 diosgenin CAS#:1061-54-7 diosgenin, acetate
CAS#:73-34-7 6-methyloxane-2... CAS#:5934-40-7 (4Z,5Z)-4,5-bis...

(3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-β-D-glucopyranoside

Desacetylophiopogonin B'

Ophiopogonin D`

β-D-glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->;3)]-

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Ophiopogonin D'

Use of Ophiopogonin D'

Names

Ophiopogonin D' Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.