Lisofylline

Modify Date: 2024-01-12 10:25:03

Lisofylline Structure
Lisofylline structure
Common Name Lisofylline
CAS Number 6493-06-7 Molecular Weight 280.323
Density 1.3±0.1 g/cm3 Boiling Point 511.2±56.0 °C at 760 mmHg
Molecular Formula C13H20N4O3 Melting Point 123-125ºC
MSDS Chinese USA Flash Point 263.0±31.8 °C

 Use of Lisofylline


(±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research[1].

 Names

Name (±)-Lisofylline
Synonym More Synonyms

 Lisofylline Biological Activity

Description (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research[1].
Related Catalog
References

[1]. Yang Z, et al. Lisofylline: a potential lead for the treatment of diabetes. Biochem Pharmacol. 2005 Jan 1;69(1):1-5.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 511.2±56.0 °C at 760 mmHg
Melting Point 123-125ºC
Molecular Formula C13H20N4O3
Molecular Weight 280.323
Flash Point 263.0±31.8 °C
Exact Mass 280.153534
PSA 82.05000
LogP 0.34
Appearance of Characters solid | white
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.621
Storage condition Refrigerator
Water Solubility DMSO: soluble

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~91%

Lisofylline Structure

Lisofylline

CAS#:6493-06-7

Literature: Kala, Elzbieta P.; Wojcik, Tomasz Acta Poloniae Pharmaceutica - Drug Research, 2007 , vol. 64, # 2 p. 109 - 113

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles1

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 Synonyms

R-1-(5-Hydroxyhexyl)-3,7-dimethylxanthine
(R)-3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione
1-[(5R)-5-Hydroxyhexyl]-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Penthydroxifillyne
HYDROXY PENTOXIFYLLINE
Lisofylline
1-(5-Hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
1H-Purine-2,6-dione, 3,7-dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-
UNII:R99EE080JS
1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-
ProTec
1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-, (R)-
1-[(R)-5-Hydroxyhexyl]theobromine
CT 1501R
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  • DC Chemicals Limited
  • China
  • Product Name: LSF
  • Price: ¥Inquiry/1g
  • Purity: 98.9%
  • Stocking Period: 1 Day
  • Contact: Tony Cao

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