Quinoxaline-d4

Modify Date: 2024-01-22 10:54:03

Quinoxaline-d4 Structure
Quinoxaline-d4 structure
Common Name Quinoxaline-d4
CAS Number 64252-08-0 Molecular Weight 134.17100
Density N/A Boiling Point N/A
Molecular Formula C8H2D4N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Quinoxaline-d4


Quinoxaline-d4 is the deuterium labeled Quinoxaline[1]. Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics[2].

 Names

Name quinoxaline-5,6,7,8-d4

 Quinoxaline-d4 Biological Activity

Description Quinoxaline-d4 is the deuterium labeled Quinoxaline[1]. Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Mónica Vieira, et al. Antimicrobial activity of quinoxaline 1,4-dioxide with 2- and 3-substituted derivatives. Microbiol Res. 2014 Apr;169(4):287-93.  

 Chemical & Physical Properties

Molecular Formula C8H2D4N2
Molecular Weight 134.17100
Exact Mass 134.07800
PSA 25.78000
LogP 1.62980