64252-08-0

64252-08-0 structure
64252-08-0 structure
  • Name: Quinoxaline-d4
  • Chemical Name: quinoxaline-5,6,7,8-d4
  • CAS Number: 64252-08-0
  • Molecular Formula: C8H2D4N2
  • Molecular Weight: 134.17100
  • Catalog: Research Areas Infection
  • Create Date: 2018-02-15 08:00:00
  • Modify Date: 2024-01-22 10:54:03
  • Quinoxaline-d4 is the deuterium labeled Quinoxaline[1]. Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics[2].

Name quinoxaline-5,6,7,8-d4
Description Quinoxaline-d4 is the deuterium labeled Quinoxaline[1]. Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Mónica Vieira, et al. Antimicrobial activity of quinoxaline 1,4-dioxide with 2- and 3-substituted derivatives. Microbiol Res. 2014 Apr;169(4):287-93.  

Molecular Formula C8H2D4N2
Molecular Weight 134.17100
Exact Mass 134.07800
PSA 25.78000
LogP 1.62980